Mark P. Farrell


Mark Farrell
  • Assistant Professor
  • Department of Medicinal Chemistry

Contact Info

Shankel Stuctural Biology Center, Room 2059
2030 Becker Drive
Lawrence, KS 66047

Education

Ph.D. in Synthetic Organic Chemistry, National University, Ireland
B.S. in Chemistry, 1st Class Honours, National University, Ireland

Selected Publications

Influence of acyl groups on glucopyranoside reactivity in Lewis acid promoted anomerizations. Tett. Lett., 2018, 59, 2727-2731.

Herschhorn, A. Gu, C. Moraca, F. Ma, X. Farrell, M. Smith, A. B., Pancera, M. Kwong, P. D., Schön, A. Freire, E. Abrams, C. Blanchard, S. C., Mothes, W. & Sodroski, J. G. (2017). The β20–β21 of gp120 is a regulatory switch for HIV-1 Env conformational transitions. Nature Communications, 8(1), 1049. https://doi.org/10.1038/s41467-017-01119-w

Farrell, M. Melillo, B. & Smith, A. B. (2016). Type II Anion Relay Chemistry: Exploiting Bifunctional Weinreb Amide Linchpins for the One-Pot Synthesis of Differentiated 1,3-Diketones, Pyrans, and Spiroketals. Angew. Chem. Int. Ed, 55, 232-235.

Farrell, M. O'Reilly, C. Venkatrao Jarikote, D. & Murphy, P. V. (2014). Ultrasonic Energy Promoted Allylation to Generate 1-C-(2,3,4,6-Tetra-O-benzyl-α-D-glucopyranosyl)prop-2-ene. Carbohydrate Chemistry: Proven Synthetic Methods, 2.

Breen, E. P., Pilgrim, W. Clarke, K. J., Yssel, C. Farrell, M. Zhou, J. Murphy, P. V., & Porter, R. K. (2013). Lack of Activation of UCP1 in isolated brown adipose tissue mitochondria by glucose-O-ω-modified saturated fatty acids of various chain lengths. J. Chem. Biol, 6, 121-133.

Farrell, M. Zhou, J. & Murphy, P. V. (2013). Regiospecific anomerisation of acylated glycosyl azides and benzoylated disaccharides using TiCl4. Chem. Eur. J, 13, 14836-14851

Gerlach, J. Kilcoyne, M. Farrell, M. Kane, M. & Joshi, L. (2012). Differential release of high mannose structural isoforms by fungal and bacterial endo-β-N-acetylglucosaminidases. Mol. BioSyst, 8, 1472-1481

Kilcoyne, M. Gerlach, J. Farrell, M. Bhavanandan, V. & Joshi, L. (2011). Periodic acid-Schiff’s reagent assay for carbohydrates in a microtiter plate format. Anal. Biochem, 1, 18-26

Awards & Honors

  • Boc gas Postgraduate Student of the Year (2014)
  • Galway Graduate Symposium Winner, Eli-Lilly NUI (2012)
  • IRCSET Enterprise Ph.D. Fellowship (2010)
  • SFI UREKA (Undergraduate Research Experience & Knowledge Award) Scholarship (2009)