Mark Farrell

  • Assistant Professor
  • School of Pharmacy - Medicinal Chemistry
785-864-6234
Office
Shankel Stuctural Biology Center
2030 Becker Drive
Lawrence, 66047

Education

  • Ph.D., Synthetic Organic Chemistry, National University, Ireland
  • B.S., Chemistry, 1st Class Honours, National University, Ireland

Publications

Selected Publications

Influence of acyl groups on glucopyranoside reactivity in Lewis acid promoted anomerizations. Tett. Lett., 2018, 59, 2727-2731.

Herschhorn, A. Gu, C. Moraca, F. Ma, X. Farrell, M. Smith, A. B., Pancera, M. Kwong, P. D., Schön, A. Freire, E. Abrams, C. Blanchard, S. C., Mothes, W. & Sodroski, J. G. (2017). The β20–β21 of gp120 is a regulatory switch for HIV-1 Env conformational transitions. Nature Communications, 8(1), 1049. DOI:10.1038/s41467-017-01119-w https://doi.org/10.1038/s41467-017-01119-w

Farrell, M. Melillo, B. & Smith, A. B. (2016). Type II Anion Relay Chemistry: Exploiting Bifunctional Weinreb Amide Linchpins for the One-Pot Synthesis of Differentiated 1,3-Diketones, Pyrans, and Spiroketals. Angew. Chem. Int. Ed, 55, 232-235.

Farrell, M. O'Reilly, C. Venkatrao Jarikote, D. & Murphy, P. V. (2014). Ultrasonic Energy Promoted Allylation to Generate 1-C-(2,3,4,6-Tetra-O-benzyl-α-D-glucopyranosyl)prop-2-ene. Carbohydrate Chemistry: Proven Synthetic Methods, 2.

Breen, E. P., Pilgrim, W. Clarke, K. J., Yssel, C. Farrell, M. Zhou, J. Murphy, P. V., & Porter, R. K. (2013). Lack of Activation of UCP1 in isolated brown adipose tissue mitochondria by glucose-O-ω-modified saturated fatty acids of various chain lengths. J. Chem. Biol, 6, 121-133.

Farrell, M. Zhou, J. & Murphy, P. V. (2013). Regiospecific anomerisation of acylated glycosyl azides and benzoylated disaccharides using TiCl4. Chem. Eur. J, 13, 14836-14851

Gerlach, J. Kilcoyne, M. Farrell, M. Kane, M. & Joshi, L. (2012). Differential release of high mannose structural isoforms by fungal and bacterial endo-β-N-acetylglucosaminidases. Mol. BioSyst, 8, 1472-1481

Kilcoyne, M. Gerlach, J. Farrell, M. Bhavanandan, V. & Joshi, L. (2011). Periodic acid-Schiff’s reagent assay for carbohydrates in a microtiter plate format. Anal. Biochem, 1, 18-26

Awards & Honors

  • Boc gas Postgraduate Student of the Year (2014)
  • Galway Graduate Symposium Winner, Eli-Lilly NUI (2012)
  • IRCSET Enterprise Ph.D. Fellowship (2010)
  • SFI UREKA (Undergraduate Research Experience & Knowledge Award) Scholarship (2009)

Events
2nd among all schools of pharmacy in National Institutes of Health funding
Brings more than $20 million in external funding into the state each year
7 of 19 cancer drugs formulated through the National Cancer Institute were developed at the KU School of Pharmacy
3,000 free flu shots given to Kansans in need during the past 5 years
4,000 living alumni, 63 percent of them living and working in Kansas
KU pharmacists practice in 95 of Kansas’ 105 counties
20th among public schools of pharmacy.
—U.S. News & World Report
$20.2 million NIH research grant earned by Distinguished Professor Jeff Aubé was 2nd largest in Kansas history
100 percent placement after graduation for KU Pharm.D. students
Established in 1885 as the 1st professional program at KU