Kenneth L. (“Ken”) Audus holds a B.S. degree in Chemistry from the University of South Dakota in 1980 and a Ph.D. in Pharmacology from the University of Kansas Medical Center in 1984. After completing postdoctoral work in Pharmaceutical Chemistry at the University of Kansas, he joined the faculty of that Department in 1986 and worked his way up through the academic ranks to become a Full Professor in 1996 and then Chair of the Department in 1998. Dr. Audus became Dean of the School of Pharmacy in April of 2004.
Dr. Audus is an Editor for the Journal of Pharmaceutical Sciences and is a member the editorial board of the International Journal of Pharmaceutics. He serves as a consultant and on the Board of Trustees and/or Directors of a number of private and public foundations. Dr. Audus is a Fellow of the American Association of Pharmaceutical Scientists and he has been recognized as an American Association of Colleges of Pharmacy Teacher of the Year and for Excellence in Undergraduate Teaching for Pharmaceutical Chemistry at the University of Kansas. Dr. Audus is the author or co-author of more than165 research articles, one patent, and the co-editor of one book on these topics.
Dean Audus’ research interests have included the development and application of cell culture models to study drug distribution across the blood-brain barrier for the treatment of tumors and Alzheimer’s disease, and human trophoblast culture systems for studying how drug distribution across the placenta might be controlled and provide for safer drugs for mother and the fetus during pregnancy.
- Blood-brain barrier
- Placental barrier
- In vitro models
- Drug delivery.
Joshi, A. A, Vaidya, S. S, St-Pierre, M. V, Mikheev, A. M, Nyandege, A. N, Audus, K. L, Unadkat, J. D, & Gerk, P. M (2016). Placental ABC Transporters: Biological Impact and Pharmaceutical Significance. Pharmaceutical research. DOI:10.1007/s11095-016-2028-8
Kuhnline Sloan, C. D., Nandi, P., Linz, T. H., Aldrich, J. V., Audus, K. L., & Lunte, S. M. (2012). Analytical and biological methods for probing the blood-brain barrier. Annu Rev Anal Chem, 5, 505–531. DOI:10.1146/annurev-anchem-062011-143002
Audus, K. L., Moreton, J. E., Normann, S. A., Sands, C. D., Seaba, H. H., Wincor, M. Z., Sagraves, R., & Miller, K. W. (2010). Going global: the report of the 2009-2010 Research and Graduate Affairs Committee. Am J Pharm Educ, 74(10), S8.
Audus' research interests focused on the application of endothelial and epithelial cell and tissue culture systems to study mechanisms of drug transport, metabolism, and tissue permeability regulation. His research included establishment of tissue culture systems comprised of brain microvessel endothelium (i.e., the blood-brain barrier) and trophoblasts (i.e., the placental barrier).
Audus served as chair of the Department of Pharmaceutical Chemistry for six years prior to his appointment as dean in 2004.