Jingxin Wang

  • Assistant Professor
  • School of Pharmacy - Medicinal Chemistry
785-864-XXXX
Office
Wescoe Hall
University of Kansas
1251 Wescoe Hall Drive
Lawrence, KS 66047

Education

  • Postdoctoral Fellow, Johns Hopkins University (2014) and Scripps Research Institute (2019)
  • Ph.D., Chemistry, University of Maryland (2011)
  • B.S., Chemistry, Peking University (2006)

Research Overview

The Wang laboratory is focused on:

  • A novel pharmacological modality of modulating RNA splicing by small molecules
  • Exploring new approaches to regulate innate immune response in mammalian cells.

Publications

Selected Publications

Rapafucins, rapamycin-inspired macrocycles with new target specificity. (2019) Nat. Chem.,11(3):254-63. Guo ZF#, Hong SY#, Wang J#, Rehan S, Liu W, Peng H, Das M, Li W, Bhat S, Peiffer B, Ullman BR, Tse CM, Tarmakova Z, Schiene-Fischer C, Fischer G, Coe I, Paavilainen VO, Sun Z, Liu JO. (# = co-first authors).

Mechanistic studies of a small molecule modulator of SMN2 splicing, PNAS, 115(20): E4604-12. (2018) Wang J, Schultz PG, Johnson K.

Conservative change to the phosphate moiety of cyclic diguanylic monophosphate remarkably affects its polymorphism and ability to bind DGC, PDE, and PilZ proteins. J. Am. Chem. Soc. 133(24):9320-90. (2011) Wang J, Zhou J, Donaldson GP, Nakayama S, Yan L, Lam YF, Lee VT, Sintim HO.


Events
2nd among all schools of pharmacy in National Institutes of Health funding
Brings more than $20 million in external funding into the state each year
7 of 19 cancer drugs formulated through the National Cancer Institute were developed at the KU School of Pharmacy
3,000 free flu shots given to Kansans in need during the past 5 years
4,000 living alumni, 63 percent of them living and working in Kansas
KU pharmacists practice in 95 of Kansas’ 105 counties
20th among public schools of pharmacy.
—U.S. News & World Report
$20.2 million NIH research grant earned by Distinguished Professor Jeff Aubé was 2nd largest in Kansas history
100 percent placement after graduation for KU Pharm.D. students
Established in 1885 as the 1st professional program at KU